Dr. Mahmoud Marashi, Head of Hematology Unit Consultant Physician/Clinical Haematologist Rashid Hospital, Dubai, United Arab Emirates discusses the evolvement of CLL management. Dr. Mahmoud Marashi initially started with the basics of CLL/SLL. He gives an impact of TP53 aberrations in CLL patients prior to novel targeted therapies. Dr. Mahmoud Marashi also gives an overview for somatic hyper-mutation of Ig-gene. He provides a brief regarding current therapies in CLL/SLL, BTK inhibitors in treatment -Naïve CLL and in R/R CLL by giving few trial data along with few potential AEs. He also discusses about BCL-2 inhibitor. He highlighted the impact of combination therapy in the treatment and as a promising agent in the future.

 

 

Explore more videos

Translating Data Into Clinical Practice

Dr. Abdulkareem Algarni, KSA

Critical Evaluation of BTKis in CLL

Dr. George Follows, UK

CLL Management Inside the Clinic

Dr. Hani Yousif Osman , UAE